Technology

Our Solution

ClotGuard is an integrated bleeding control system designed for rapid, autonomous response in emergency situations.

Real-Time Detection

Uses biosensors to detect key bleeding indicators such as thrombin levels and oxygen changes. Continuous monitoring ensures no critical moment is missed.

Autonomous Activation

No manual input required — the system responds instantly when thresholds are met. Automated response eliminates the delay of human reaction time.

Targeted Delivery

Delivers clotting agents directly to the wound site using a controlled microneedle system. Precise targeting ensures maximum effectiveness with minimal waste.

Biocompatible Design

Built using safe, biodegradable materials to ensure compatibility within the human body. Every component is designed for safety and minimal side effects.

3D visualization of blood cells and clotting factors
How It Works

Intelligent Bleeding Response

Our system combines advanced biosensing technology with an automated microneedle delivery mechanism. When bleeding indicators exceed safe thresholds, ClotGuard activates without any human intervention.

The targeted delivery system ensures that clotting agents reach the wound site precisely and rapidly, providing life-saving treatment in the critical moments before emergency services arrive.

Why Now

The Need Has Never Been Greater

Rising trauma cases and persistent delays in emergency care highlight the urgent need for autonomous bleeding control. Advances in biosensor technology, biocompatible materials, and microneedle delivery systems have finally made this possible.

Reduce Preventable Deaths

Target the leading cause of preventable death in trauma situations worldwide.

Faster Emergency Response

Enable life-saving treatment in the critical moments before first responders arrive.

Global Accessibility

A wearable solution that can be deployed anywhere, from urban centers to remote areas.

At a Glance

The ClotGuard One-Pager

Everything you need to know about ClotGuard in a single page. From our freeze-dried platelet technology and nanobot-powered delivery system to real-world impact metrics, this document covers how ClotGuard works and why it matters.

Download our one-pager for a comprehensive overview of the technology, our process, and the advantages ClotGuard brings to emergency bleeding control.

Download One-Pager (PDF)
Research Foundation

Validated by Science

ClotGuard's concept is grounded in over 100 peer-reviewed publications spanning stimuli-responsive drug delivery, platelet-membrane biomimetics, hemostatic nanomaterials, and biosensor-triggered therapeutics. Beyond the literature, we have consulted with dozens of professors and PhD holders in biomedical engineering, hematology, and nanotechnology who have validated our approach.

Stimuli responsiveness of recent biomacromolecular systems (concept to market): A review

Singh, D., Sharma, Y., Dheer, D., Shankar, R.

International Journal of Biological Macromolecules, 2024

Platelet-derived membranes as biomimetic interfaces for engineering functional nanocarriers

Coradduzza, D., Vecciu, B., Cadoni, M.P.L., et al.

Biomaterials Science, 2025

Nano-safety guardians: Surface engineering strategies for building hemocompatible shields

Cai, X., Chen, H., Peng, Z., et al.

Applied Surface Science Advances, 2025

A Sprayable Hydrogel Based on Biomimetic Polypeptide-Modified Lipid Nanoparticles for Non-Compressible Hemorrhaging

Feng, Y., Zhang, Z., Yan, W., et al.

Advanced Materials, 2025

Modulating Nanoparticle Size to Understand Factors Affecting Hemostatic Efficacy

Hong, C., Alser, O., Gebran, A., et al.

ACS Nano, 2022

Intraosseous administration of lyophilized synthetic platelets renders hemostatic efficacy

Liu, Z., Abdullah, A., Secunda, Z.A., et al.

Journal of Thrombosis and Haemostasis, 2025

Modulating Coagulation via Bioinspired Mesoporous Calcium-Decorated Silica Nanoparticles

Ms, M., Venkatasubbu, G.D.

ACS Applied Bio Materials, 2024

Calcium-based nanoparticles accelerate skin wound healing

Kawai, K., Larson, B.J., Ishise, H., et al.

PLoS ONE, 2011

Controllable Thrombolysis Using a Nanobubble-Imaging-Guided rtPA Targeted Delivery Strategy

Tang, J., Xu, H., Li, M., et al.

BME Frontiers, 2024

From bench to bedside: Platelet biomimetic nanoparticles as promising carriers for personalized drug delivery

Safdar, A., Wang, P., Muhaymin, A., et al.

Journal of Controlled Release, 2024

Porous gelatin microspheres for controlled drug delivery with high hemostatic efficacy

Cao, S., Li, L., Du, Y., et al.

Colloids and Surfaces B: Biointerfaces, 2021

Targeted Hybrid Theranostic Nanocarriers Enhance Thrombolytic Therapy

Gao, M., Lu, J., Liang, J., et al.

ACS Applied Materials and Interfaces, 2025

Showing 12 of 112 referenced publications. Our full reference list spans stimuli-responsive drug delivery, platelet-membrane biomimetics, calcium-based hemostatics, nanocarrier engineering, and wound-responsive smart materials.